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Rheumatoid arthritis & osteo arthritis

  Rheumatoid arthritis Osteoarthritis
Definition Rheumatoid arthritis is a chronic inflammatory condition. It is an auto immune disorder. Osteoarthritis is a condition due to breakdown of joint cartilage. It is a degenerative disorder.
Causes Exact cause not known Joint injury, obesity, extreme joint movement
Joint involvement Multiple joints affected (At least 3 small joints) joints affected in a symmetrical way Single & majority large (weight bearing) joint affected joints affected may be on one side of the body
Symptoms Stiffness, painful and swollen joints Relief in pain after movement Erythematous & warmness Pain and mild tenderness of joints pain increases after movement
Speed of onset Rapid Slow, over a period of time
Severity More severe Less severe
Investigations Blood test – CBC, ESR, CRP, ANA (Anti Nuclear Antibody), Anti-CCPA (Anti-Cyclic Citrullinated peptide Antibody)

RA Factor +ve in Blood


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